教員プロフィール

三熊 敏靖

三熊 敏靖 講師

三熊 敏靖

薬は諸刃の剣。
正しい知識と高い倫理観を持った薬剤師を目指して。

薬は、いつも人を助ける良き化合物でしょうか。残念ながら違います。薬物乱用に代表されるように、薬は用途を間違えると、人の人生をむしばむ危険な化合物となります。
薬は、皆さんが思っている以上に人の人生を動かす大きな力を持っているのです。
この「薬」を扱うプロフェッショナルを目指し、本学で6年間学んでみませんか。皆さんが将来、正しい知識と責任感を持った薬剤師になるために、我々は全力でサポートを続けます。

略歴

博士(薬科学)
筑波大学第一学群自然学類化学専攻卒業
慶應義塾大学大学院薬学研究科後期博士課程修了
千葉県警察本部科学捜査研究所主任研究員を経て現職

学術論文

  • Mikuma T., Kuroki T., Yoshikawa M., Uchida R., Hiruta Y., Kanazawa H. Analysis of psychoactive drugs by temperature-responsive chromatography, Chromatography. 38(3): 115-121, 2017.
  • Mikuma T., Uchida R., Kajiya M., Hiruta Y., Kanazawa H. The use of a temperature-responsive column for the direct analysis of drugs in serum by two-dimensional heart-cutting liquid chromatography, Analytical and Bioanalytical Chemistry. 409: 1059-65, 2017.
  • Mikuma T., Iwata Y.T., Miyaguchi H., Kuwayama K., Tsujikawa K., Kanamori T., Kanazawa H., Inoue H. Approaching over 10 000-fold sensitivity increase in chiral capillary electrophoresis: cation-selective exhaustive injection and sweeping cyclodextrin-modified micellar electrokinetic chromatography, Electrophoresis. 37(22): 2970-6, 2016.
  • Yoshikawa M., Uchida R., Kuroki T., Mikuma T., Hiruta Y., Nagata Y., Kanazawa H. Rapid and simultaneous analysis of psychotropic drugs by ultra-high-speed HPLC, Bunseki Kagaku. 65(4): 173-9, 2016.
  • Mikuma T., Iwata Y.T., Miyaguchi H., Kuwayama K., Tsujikawa K., Kanamori T., Inoue H. The use of a sulfonated capillary on chiral capillary electrophoresis/mass spectrometry of amphetamine-type stimulants for methamphetamine impurity profiling, Forensic Science International. 249: 59-65, 2015.
  • Iwata Y.T., Mikuma T., Miyaguchi H., Kuwayama K., Tsujikawa K., Kanamori T., Inoue H. Chiral capillary electrophoresis of amphetamine-type stimulants, Electrophoresis Letters. 59(2): 64-6, 2015.
  • Iwata Y.T., Mikuma T., Kuwayama K., Tsujikawa K., Miyaguchi H., Kanamori T., Inoue H. Applicability of chemically modified capillaries in chiral capillary electrophoresis for methamphetamine profiling, Forensic Science International. 226(1-3): 235-9, 2013.
  • Tsujikawa K., Mikuma T., Kuwayama K., Miyaguchi H., Kanamori T., Iwata Y.T., Inoue H. Identification and differentiation of methcathinone analogs by gas chromatography-mass spectrometry, Drug Testing and Analysis. 5(8): 670-7, 2013.
  • Tsujikawa K., Mikuma T., Kuwayama K., Miyaguchi H., Kanamori T., Iwata Y.T., Inoue H. Degradation pathways of 4-methylmethcathinone in alkaline solution and stability of methcathinone analogs in various pH solutions, Forensic Science International. 220(1-3): 103-10, 2012.
  • Tsujikawa K., Mikuma T., Kuwayama K., Miyaguchi H., Kanamori T., Iwata Y.T., Inoue H. Profiling of seized methamphetamine putatively synthesized by reductive amination of 1-phenyl-2-propanone, Forensic Toxicology. 30(1): 70-5, 2012.
  • Tsujikawa K., Mikuma T., Kuwayama K., Miyaguchi H., Kanamori T., Iwata Y.T., Inoue H. Urinary excretion profiles of N-hydroxy-3,4-methylenedioxymethamphetamine in rats, Xenobiotica. 41(7): 578-84, 2011.
  • Mikuma T., Kaneko T. A quick discrimination of vegetable oil by solid-phase microextraction method, Forensic Science International. 198(1-3): 79-84, 2010.
  • Mikuma T., Kaneko T. Forensic discrimination of vegetable oils using direct detection of acylglycerols by liquid chromatography/mass spectrometry, Bunseki Kagaku. 59(5): 399-404, 2010.
  • Uddin M.K., Kato Y., Takagi Y., Mikuma T., Taira K. Phosphorylation at 5' end of guanosine stretches inhibits dimerization of G-quadruplexes and formation of a G-quadruplex interferes with the enzymatic activities of DNA enzymes, Nucleic Acids Research. 32(15): 4618-29, 2004.
  • Mikuma T., Kawasaki H., Yamamoto Y., Taira K. Overexpression of Dicer enhances RNAi-mediated gene silencing by short-hairpin RNAs (shRNAs) in human cells, Nucleic Acids Symp Ser (Oxf). (48): 191-2, 2004.
  • Mikuma T., Ohyama T., Terui N., Yamamoto Y., Hori H. Coordination complex between haemin and parallel-quadruplexed d(TTAGGG), Chemical Communications (Camb). (14): 1708-9, 2003.
  • Mikuma T., Terui N., Yamamoto Y., Hori H. A novel heme-DNA coordination complex and its stability, Nucleic Acids Research Suppl. (2): 285-6, 2002.