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IWASE Harunobu, M.S. / Assistant Professor

Pharmaceutical Business Sciences Course · Pharmaceutical Information Sciences Course

Department of Pharmaceutical and Medical Business Sciences

Research Topics

1. Biological Effects of the Plasticizer Tris (2-Ethylhexyl) Trimellitate.

An alternative plasticizer, tris (2-ethylhexyl) trimellitate (TOTM), was developed from di-(2-ethylhexyl) phthalate (DEHP) for use in medical tubing. However, little is known about the biological effects of TOTM and thus its safety is not yet wellestablished. Our group studies about the biological effects of TOTM and thus its safety.

Representative Publications

1. Iwase H, Oiso S, Kariyazono H, Nakamura K; Nutritional Effect of Oral Supplement Enriched in ω-3 Fatty Acids, Arginine, RNA on Immune Response and Leukocyte–platelet Aggregate Formation in Patients Undergoing Cardiac Surgery. Nutr Metab Insights., 7, 39-46 (2014).

2. Iwase H, Oiso S, Kariyazono H, Nakamura K.; Biological Effects of the Plasticizer Tris (2-Ethylhexyl) Trimellitate. Clin Pharmacol Biopharm., S2:004. doi: 10.4172/2167-065X.S2-004 (2014).

3. Iwase H, Kariyazono H, Arima J, Yamamoto H, Nakamura K.; Relationship between Platelet Aggregatory and Heparin- Induced Thrombocytopenia Type II. Science Research, 2(4):78-86 (2014).